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Diazepam is a member of the
benzodiazepine family. Benzodiazepines are sedatives
that cause dose-related depression of the central
nervous system. They are useful in treating anxiety,
insomnia, seizures, and muscle spasms.
Diazepam is used for the short-term relief of symptoms
related to anxiety disorders. Diazepam is also used for
the treatment of agitation, tremors, delirium, seizures,
and hallucinations as a result of alcohol withdrawal.
Diazepam is also used for relief of muscle spasms in
certain neurological diseases. Diazepam is used to abort
active seizures and can be combined with other drugs in
treating severe recurrent seizures.
Diazepam may be taken with or without food. Diazepam is
metabolized by the liver and excreted mainly by the
kidney. Dosages of diazepam may need to be lowered in
patients with abnormal kidney function.
Valium
Precautions
Alcohol should be avoided by patients taking
benzodiazepines. Diazepam can lead to addiction
(dependency), especially at higher dosages over
prolonged periods of time. Because of diazepam's
addicting potential, dosages should never be increased
by the patient. In patients addicted to diazepam, abrupt
discontinuation of the medicine can lead to symptoms of
withdrawal (insomnia, headaches, nausea, vomiting,
lightheadedness, sweating, anxiety, and fatigue).
Seizures can occur in more severe cases of withdrawal.
Consequently, patients on diazepam for extended periods
of time should slowly taper the medication under a
doctor's supervision rather than abruptly stopping the
medication. Benzodiazepines, such as diazepam, can cause
fetal problems and should not be used in pregnancy or in
breast feeding mothers. Tagamet can prolong the effects
of diazepam and dosages may need to be decreased when
these drugs are used together.
Valium Side
Effects
The most frequent side effects of diazepam are
drowsiness, fatigue, and ataxia (loss of balance).
Rarely, diazepam causes a paradoxical reaction with
excitability, muscle spasm, lack of sleep, and rage.
Confusion, depression, speech problems, and double
vision are also rare side effects of diazepam.
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